| 1 | Avengers: Endgame | 2019-04-24 | $356M | $918.37M | 2.58 |
| 2 | Spider-Man: No Way Home | 2021-12-15 | $200M | $864.8M | 4.32 |
| 3 | Black Panther | 2018-02-13 | $200M | $725.26M | 3.63 |
| 4 | Avengers: Infinity War | 2018-04-25 | $300M | $717.82M | 2.39 |
| 5 | The Super Mario Bros. Movie | 2023-04-05 | $100M | $574.93M | 5.75 |
| 6 | The Lion King | 2019-07-12 | $260M | $566.64M | 2.18 |
| 7 | Guardians of the Galaxy Vol. 2 | 2017-04-19 | $200M | $406.81M | 2.03 |
| 8 | Suicide Squad | 2016-08-03 | $175M | $345.6M | 1.97 |
| 9 | Sing | 2016-11-23 | $75M | $272.03M | 3.63 |
| 10 | Justice League | 2017-11-15 | $300M | $242.02M | 0.81 |
| 11 | The Fate of the Furious | 2017-04-12 | $250M | $236.16M | 0.94 |
| 12 | Ant-Man and the Wasp | 2018-07-04 | $140M | $228.15M | 1.63 |
| 13 | Mission: Impossible - Fallout | 2018-07-13 | $178M | $226.16M | 1.27 |
| 14 | Wonka | 2023-12-06 | $125M | $221.9M | 1.78 |
| 15 | Thunderbolts* | 2025-04-30 | $180M | $201.77M | 1.12 |
| 16 | John Wick: Chapter 4 | 2023-03-22 | $90M | $196.03M | 2.18 |
| 17 | Fantastic Beasts: The Crimes of Grindelwald | 2018-11-14 | $200M | $168.66M | 0.84 |
| 18 | Knives Out | 2019-11-27 | $40M | $167.02M | 4.18 |
| 19 | Weapons | 2025-08-04 | $38M | $157.25M | 4.14 |
| 20 | Fast X | 2023-05-17 | $340M | $153.46M | 0.45 |
| 21 | Once Upon a Time... in Hollywood | 2019-07-24 | $95M | $148.29M | 1.56 |
| 22 | Mamma Mia! Here We Go Again | 2018-07-09 | $75M | $124.03M | 1.65 |
| 23 | Smile | 2022-09-23 | $17M | $107.94M | 6.35 |
| 24 | Pitch Perfect 3 | 2017-12-20 | $45M | $104.9M | 2.33 |
| 25 | Murder on the Orient Express | 2017-11-03 | $55M | $104.4M | 1.90 |
| 26 | Dungeons & Dragons: Honor Among Thieves | 2023-03-23 | $151M | $98.88M | 0.65 |
| 27 | The Magnificent Seven | 2016-09-14 | $90M | $95.18M | 1.06 |
| 28 | Birds of Prey (and the Fantabulous Emancipation of One Harley Quinn) | 2020-02-05 | $75M | $88.16M | 1.18 |
| 29 | Game Night | 2018-02-15 | $37M | $69M | 1.86 |
| 30 | Into the Woods | 2014-12-24 | $50M | $62.67M | 1.25 |
| 31 | Escape Room | 2019-01-03 | $9M | $59.26M | 6.58 |
| 32 | Pacific Rim: Uprising | 2018-03-21 | $150M | $59.19M | 0.39 |
| 33 | Midway | 2019-11-06 | $100M | $57.77M | 0.58 |
| 34 | Tag | 2018-05-30 | $28M | $55.87M | 2.00 |
| 35 | The Hateful Eight | 2015-12-25 | $44M | $54.12M | 1.23 |
| 36 | Downton Abbey: The Grand Finale | 2025-09-10 | $50M | $47.6M | 0.95 |
| 37 | Red Sparrow | 2018-02-28 | $69M | $46.74M | 0.68 |
| 38 | Almost Christmas | 2016-11-11 | $17M | $42.57M | 2.50 |
| 39 | Uncle Drew | 2018-06-27 | $19M | $42.47M | 2.24 |
| 40 | The Angry Birds Movie 2 | 2019-08-02 | $65M | $41.66M | 0.64 |
| 41 | 80 for Brady | 2023-02-03 | $28M | $40.08M | 1.43 |
| 42 | The Gentlemen | 2020-01-01 | $22M | $37.2M | 1.69 |
| 43 | The Second Best Exotic Marigold Hotel | 2015-02-26 | $10M | $33.02M | 3.30 |
| 44 | Mother's Day | 2016-04-28 | $25M | $32.49M | 1.30 |
| 45 | Patriots Day | 2016-12-12 | $45M | $31.89M | 0.71 |
| 46 | Smurfs | 2025-07-05 | $58M | $31.07M | 0.54 |
| 47 | Collateral Beauty | 2016-12-15 | $36M | $31.02M | 0.86 |
| 48 | Hail, Caesar! | 2016-02-05 | $22M | $30.62M | 1.39 |
| 49 | Super Troopers 2 | 2018-04-19 | $14M | $30.61M | 2.27 |
| 50 | Horizon: An American Saga - Chapter 1 | 2024-06-26 | $50M | $29.84M | 0.60 |