| 1 | Spider-Man: No Way Home | 2021-12-15 | $200M | $864.8M | 4.32 |
| 2 | Avengers: Infinity War | 2018-04-25 | $300M | $717.82M | 2.39 |
| 3 | Avatar: The Way of Water | 2022-12-14 | $350M | $705.81M | 2.02 |
| 4 | Jurassic World | 2015-06-06 | $150M | $670.7M | 4.47 |
| 5 | Star Wars: The Last Jedi | 2017-12-13 | $200M | $665.18M | 3.33 |
| 6 | Barbie | 2023-07-19 | $145M | $658.54M | 4.54 |
| 7 | Incredibles 2 | 2018-06-14 | $200M | $627.08M | 3.14 |
| 8 | Beauty and the Beast | 2017-03-16 | $160M | $520.31M | 3.25 |
| 9 | Finding Dory | 2016-06-16 | $200M | $495.5M | 2.48 |
| 10 | Moana 2 | 2024-11-21 | $150M | $474.21M | 3.16 |
| 11 | Doctor Strange in the Multiverse of Madness | 2022-05-04 | $200M | $447.33M | 2.24 |
| 12 | A Minecraft Movie | 2025-03-31 | $150M | $434.5M | 2.90 |
| 13 | Jurassic World: Fallen Kingdom | 2018-06-06 | $170M | $432.07M | 2.54 |
| 14 | Wonder Woman | 2017-05-30 | $149M | $423.56M | 2.84 |
| 15 | Guardians of the Galaxy Vol. 2 | 2017-04-19 | $200M | $406.81M | 2.03 |
| 16 | Jumanji: Welcome to the Jungle | 2017-12-09 | $90M | $402.65M | 4.47 |
| 17 | Spider-Man: Across the Spider-Verse | 2023-05-31 | $100M | $398.94M | 3.99 |
| 18 | Minions: The Rise of Gru | 2022-06-29 | $85M | $380.25M | 4.47 |
| 19 | Deadpool | 2016-02-09 | $58M | $375.74M | 6.48 |
| 20 | Thor: Love and Thunder | 2022-07-06 | $250M | $372.26M | 1.49 |
| 21 | Despicable Me 4 | 2024-06-20 | $100M | $361M | 3.61 |
| 22 | American Sniper | 2014-12-25 | $59M | $359.35M | 6.11 |
| 23 | Inside Out | 2015-06-17 | $175M | $357.55M | 2.04 |
| 24 | Spider-Man: Homecoming | 2017-07-05 | $175M | $349.97M | 2.00 |
| 25 | Joker | 2019-10-01 | $55M | $348.75M | 6.34 |
| 26 | Minions | 2015-06-17 | $74M | $342.25M | 4.62 |
| 27 | Wicked: For Good | 2025-11-19 | $150M | $311.22M | 2.07 |
| 28 | The Fantastic Four: First Steps | 2025-07-23 | $200M | $298.69M | 1.49 |
| 29 | Sing | 2016-11-23 | $75M | $272.03M | 3.63 |
| 30 | Despicable Me 3 | 2017-06-15 | $80M | $268.72M | 3.36 |
| 31 | Fantastic Beasts and Where to Find Them | 2016-11-16 | $180M | $242.79M | 1.35 |
| 32 | Sonic the Hedgehog 3 | 2024-12-19 | $122M | $242.62M | 1.99 |
| 33 | The Fate of the Furious | 2017-04-12 | $250M | $236.16M | 0.94 |
| 34 | Ant-Man and the Wasp: Quantumania | 2023-02-15 | $388M | $232.01M | 0.60 |
| 35 | Mission: Impossible - Fallout | 2018-07-13 | $178M | $226.16M | 1.27 |
| 36 | Coco | 2017-10-27 | $175M | $210.46M | 1.20 |
| 37 | Godzilla x Kong: The New Empire | 2024-03-27 | $150M | $206.35M | 1.38 |
| 38 | Mission: Impossible - The Final Reckoning | 2025-05-17 | $400M | $205.71M | 0.51 |
| 39 | Ralph Breaks the Internet | 2018-11-20 | $175M | $201.09M | 1.15 |
| 40 | Black Widow | 2021-07-07 | $200M | $196.85M | 0.98 |
| 41 | John Wick: Chapter 4 | 2023-03-22 | $90M | $196.03M | 2.18 |
| 42 | Pitch Perfect 2 | 2015-05-07 | $29M | $188.39M | 6.50 |
| 43 | Ant-Man | 2015-07-14 | $130M | $184.75M | 1.42 |
| 44 | Us | 2019-03-14 | $20M | $182.41M | 9.12 |
| 45 | Indiana Jones and the Dial of Destiny | 2023-06-25 | $295M | $181.68M | 0.62 |
| 46 | Fast & Furious Presents: Hobbs & Shaw | 2019-08-01 | $200M | $179.61M | 0.90 |
| 47 | The Boss Baby | 2017-03-23 | $125M | $176.47M | 1.41 |
| 48 | The Hunger Games: The Ballad of Songbirds & Snakes | 2023-11-15 | $100M | $172.1M | 1.72 |
| 49 | Mary Poppins Returns | 2018-12-13 | $130M | $171.96M | 1.32 |
| 50 | Kong: Skull Island | 2017-03-08 | $185M | $171.75M | 0.93 |