| 1 | Batman v Superman: Dawn of Justice | 2016-03-23 | $250M | $358.06M | 1.43 |
| 2 | Jurassic World Rebirth | 2025-07-01 | $180M | $339.64M | 1.89 |
| 3 | Ant-Man and the Wasp: Quantumania | 2023-02-15 | $388M | $232.01M | 0.60 |
| 4 | The Conjuring: Last Rites | 2025-09-03 | $55M | $186.25M | 3.39 |
| 5 | Us | 2019-03-14 | $20M | $182.41M | 9.12 |
| 6 | Gladiator II | 2024-11-05 | $310M | $178.94M | 0.58 |
| 7 | Kingdom of the Planet of the Apes | 2024-05-08 | $160M | $177.73M | 1.11 |
| 8 | Eternals | 2021-11-03 | $200M | $174.37M | 0.87 |
| 9 | Halloween | 2018-10-18 | $10M | $167.06M | 16.71 |
| 10 | The SpongeBob Movie: Sponge Out of Water | 2015-01-28 | $74M | $162.99M | 2.20 |
| 11 | Once Upon a Time... in Hollywood | 2019-07-24 | $95M | $148.29M | 1.56 |
| 12 | Nope | 2022-07-20 | $68M | $129.68M | 1.91 |
| 13 | Aquaman and the Lost Kingdom | 2023-12-20 | $205M | $128.98M | 0.63 |
| 14 | The Flash | 2023-06-13 | $220M | $117.83M | 0.54 |
| 15 | Glass | 2019-01-16 | $20M | $111.04M | 5.55 |
| 16 | Independence Day: Resurgence | 2016-06-22 | $165M | $107.12M | 0.65 |
| 17 | Annabelle: Creation | 2017-08-03 | $15M | $106.09M | 7.07 |
| 18 | Murder on the Orient Express | 2017-11-03 | $55M | $104.4M | 1.90 |
| 19 | Arrival | 2016-11-10 | $47M | $102M | 2.17 |
| 20 | Passengers | 2016-12-21 | $110M | $101.21M | 0.92 |
| 21 | Sausage Party | 2016-07-11 | $19M | $100.92M | 5.31 |
| 22 | A Wrinkle in Time | 2018-03-08 | $103M | $100.48M | 0.98 |
| 23 | M3GAN | 2022-12-28 | $12M | $97.79M | 8.15 |
| 24 | Get Hard | 2015-03-26 | $40M | $92.21M | 2.31 |
| 25 | Tomorrowland | 2015-05-19 | $190M | $92.03M | 0.48 |
| 26 | The Marvels | 2023-11-08 | $275M | $91.1M | 0.33 |
| 27 | Sisters | 2015-12-18 | $30M | $87.04M | 2.90 |
| 28 | The Emoji Movie | 2017-07-23 | $50M | $86.97M | 1.74 |
| 29 | Men in Black: International | 2019-06-12 | $110M | $83.1M | 0.76 |
| 30 | Black Phone 2 | 2025-10-15 | $30M | $79.89M | 2.66 |
| 31 | Pixels | 2015-07-16 | $88M | $79.76M | 0.91 |
| 32 | Alien: Covenant | 2017-05-09 | $97M | $78.45M | 0.81 |
| 33 | Dolittle | 2020-01-02 | $175M | $77.97M | 0.45 |
| 34 | 28 Years Later | 2025-06-18 | $60M | $76.25M | 1.27 |
| 35 | Mean Girls | 2024-01-10 | $36M | $75.65M | 2.10 |
| 36 | A Bad Moms Christmas | 2017-08-04 | $28M | $72.11M | 2.58 |
| 37 | Smile 2 | 2024-10-16 | $28M | $71.47M | 2.55 |
| 38 | Evil Dead Rise | 2023-04-12 | $15M | $69.73M | 4.65 |
| 39 | Lights Out | 2016-07-21 | $5M | $69.07M | 14.10 |
| 40 | Allegiant | 2016-03-09 | $110M | $68.58M | 0.62 |
| 41 | Black Mass | 2015-09-17 | $53M | $63.98M | 1.21 |
| 42 | Candyman | 2021-08-25 | $25M | $63.09M | 2.52 |
| 43 | Into the Woods | 2014-12-24 | $50M | $62.67M | 1.25 |
| 44 | Vacation | 2015-07-28 | $31M | $60.08M | 1.94 |
| 45 | Blockers | 2018-03-14 | $21M | $59.84M | 2.85 |
| 46 | Escape Room | 2019-01-03 | $9M | $59.26M | 6.58 |
| 47 | Pacific Rim: Uprising | 2018-03-21 | $150M | $59.19M | 0.39 |
| 48 | Tomb Raider | 2018-03-05 | $94M | $57.42M | 0.61 |
| 49 | Neighbors 2: Sorority Rising | 2016-05-04 | $35M | $57.01M | 1.63 |
| 50 | Happy Death Day | 2017-10-12 | $5M | $56.68M | 11.81 |